ABSTRACT
The addition of a nucleophile to carbon of OC occurs for the functional groups aldehydes, ketones, carboxylic acids, and carboxylic acid derivatives shown below.
Notation: R = only carbon (alkyl) or hydrogen Y = various atom groupings describing carbonyl functional groups
The nucleophilic addition reaction to a carbonyl carbon is
Y = −C(alkyl) or −H; −OH; −OCR3; −SCR3; −Cl; −Br; −OOCR; −NR2
E−Nu = electrophile/nucleophile combination; in most ENu combinations, the net E+ (electrophile) is usually H+ or Metal+×.
