Structural Pathologies of the Larynx
Essential features. The majority of malignancies of the vocal folds involve abnormalities of the squamous cell epithelial lining. Squamous cell cancer of the vocal fold is defined by invasive growth from the epithelium to deeper structures of the vocal folds including the lamina propria and the vocalis muscle. Such cancers typically begin unilaterally but can extend to the opposite vocal fold. Rarely do laryngeal cancers derive from other tissues. Examples of such rare cases include connective tissue sarcomas, adenocarcinomas, lymphomas, etc.