ABSTRACT
Solar radiation reaching the surface of the earth, and thereby the surface of our skin, contains infrared, visible, and ultraviolet radiation (UVR). The extent of an individual’s exposure to UVR varies widely depending on a multiplicity of factors, such as weather, hour of the day, season, pollution, humidity, temperature, and also geographic factors, such as altitude and latitude. Photostability is the ability to resist the influence of UVR, visible light, and heat. Development of photostable sunscreens is extremely important to preserve the UV-protective capacity and to prevent the reactive intermediates of photo-unstable filter substances behaving as photo-oxidants, when coming into direct contact with the skin. Lupus erythematosus is an autoimmune disease that is triggered and exacerbated by UVR. As a consequence, photoprotection is one of the measures in the management of the patients. Significant advances on UVA protection has been achieved due to the development of potent UVA filters and the use of novel combination of filters.
