ABSTRACT
INTRODUCTION Parkinson’s disease (PD) is one of the most common neurodegenerative disorders. Molecular biological studies have suggested that PD may be caused by multiple etiologies. Mutations of several different genes have been identified to be responsible for the different inherited forms of PD. In many of these instances, the clinical, neurochemical, neuropathological, and pharmacological characteristics bear significant similarities to that of idiopathic PD. With some mutations, the patients also exhibit cerebellar and cortical dysfunctions along with the well-established clinical features commonly noted in idiopathic PD (1).
