ABSTRACT
DEFINITION The most commonly used definition of contrastinduced nephropathy is a rise in the serum creatinine of 0.5 mg/dL. Occasionally, a 1 mg/dL rise in the serum creatinine or a 25% increase in the serum creatinine has been used. More recently, with the improved awareness of the need for estimating glomerular filtration rate (GFR) for its greater accuracy in estimating renal function over the serum creatinine, studies have started to use a 25% decrease in the GFR as the definition of contrast-induced nephropathy.
