ABSTRACT
I. Introduction ............................................................................................................ 27 II. Mixture Design Experiments ................................................................................. 29 III. Examples of Mixture Design Experiments............................................................ 31
A. Heavy Duty Liquid Detergent Optimization ............................................. 32 B. Light Duty Liquid Detergent Optimization ............................................... 39 C. Detergent Concentrate Robustness Study.................................................. 45
IV. Conclusions ............................................................................................................ 49 References ........................................................................................................................ 49
I. INTRODUCTION
Development of new cleaning formulations can be a very arduous and time-consuming task. The formulator must choose from literally hundreds of raw materials. The individual ingredients must be combined in the proper ratio to obtain the best cost performance while satisfying a myriad of physical property and stability criteria. The formulation must also be robust enough to be produced on a commercial scale with little or no rework required to meet product specifications.
