ABSTRACT

There are more than 6 million chemical compounds registered with the Chemical Abstracts Service. About 10% of these compounds are used commercially, and fewer than 1000 have been thoroughly evaluated with respect to their potential for cancer causation. In a large, ongoing study (>100 books published), the International Agency for Research on Cancer (IARC) has been evaluating carcinogenicity in humans and laboratory animals based on the following groupings: chemicals, groups of chemicals, complex mixtures, occupational exposures, behavioral and life-style exposures, biological agents, and physical agents. The IARC classifies the

evidence of carcinogenicity

into four categories.