ABSTRACT

Chitosan is a natural biopolymer obtained by deacetylation of chitin, which is produced from marine shellfi sh, such as crabs, shrimp, fungal cell walls, and other biological sources. Chemically it is a linear cationic poly(β-(1-4)-2-amino-2-deoxy--glucan) derived from chitin, a poly(β-(1-4)-2-amino-2-acetamido2-deoxy--glucan) by deacetylation. Chitosan is described in terms of the degree of deacetylation (DDA) and average molecular weight. And next to cellulose, it is the second most plentiful biomass and is already known as a biocompatible and biodegradable material. Many researchers have examined tissue response to various chitosan-based implants. Results indicate that these materials evoke minimal foreign body reactions [1].