ABSTRACT

Among the many central nervous system nuclei and cortices, the cerebellar cortex may be the most amenable, but at the same time one of the most challenging, regions for meaningful multielectrode recording. This seemingly paradoxical opening statement is due to the fact that, although the unique anatomical organization of the cerebellar cortex completely lends itself to array recording, the location and fragility of its cellular components make it highly liable to disruption by placing microelectrodes into its circuitry. Thus, the purpose of this chapter is to highlight the features

of the cerebellar cortex that lend themselves to multielectrode recording, to describe experimental methods that we have used for doing so, and to describe analytical methods and results obtained from multielectrode recording of cerebellar cortex during movement.