ABSTRACT

Notes about the scheme The ‘fear network’ is an interconnection of different anatomical brain structures thought to play a major role in the pathogenesis of anxiety disorders. Anxious behavior/disorders arise, at least in part, following pathological processing of sensory data and inadequate response of target organs to such stimuli. Specifically, viscerosensory information is conveyed to the amygdala by two major pathways: downstream, from the thalamus, and upstream, from the primary viscerosensory cortices and via corticothalamic relays allowing for higher-level neurocognitive processing and modulation of sensory information. Contextual information is stored in the hippocampus and conveyed directly to the amygdala.