ABSTRACT

Presents up-to-date concepts and approaches to the theory and practice of alternatives to animal testing and promotes technology transfer. The text addresses some of the ramifications of the National Institutes of Health Revitalization Act of 1993 which instructs the NIH to fund replacement, reduction and refinement alternatives. It also describes

part |2 pages

Part I: DERMAL TOXICITY

chapter 3|10 pages

An In Vitro Model for Skin Reconstruction

part |2 pages

Part III: IMMUNOTOXICITY

part |2 pages

Part V: ORAL/DERMAL/OCULAR VALIDATION

chapter 34|8 pages

Validation Issues for Alternatives Testing