ABSTRACT

The increase in the potency and number of new drugs has contributed immeasurably to modem drug therapy, but like all progress it has also created new problems. A problem of increasing concern is the greater incidence of adverse effects when two or more drugs are given concurrently. Interactions between drugs are predictable and avoidable, or at least manipulable. Physicians should know about potential drug interactions and take precautions to avoid adverse clinical outcomes when­ ever they prescribe or administer medications (1) (Table 7-1).