ABSTRACT

Arsenic was first recorded as a medicinal agent in ancient Greece by Hippocrates. Although it is rarely part of the modem pharmacopeia, it is widely used in other applica­ tions.

Because arsenic is nearly tasteless and odorless, it was used extensively as a means of criminal poisoning, and although not as common, homicidal, suicidal, and acci­ dental arsenic poisoning occur even today (1). Self­ administration of arsenic by accident in children and as a suicide attempt in adults represent the most common types of ingestion. Purposeful self-administration of arsenic for the purpose of creating and maintaining a state of chronic invalidism has also been reported (2). Arsenic is second only to lead as a cause of chronic heavy metal poisoning.