ABSTRACT
Since its introduction more than 35 years ago, isoniazid has been used worldwide as a synthetic antibiotic for the treatment of active pulmonary tuberculosis as well as prophylactically in patients with a positive tuberculin skin test (1). Isoniazid intoxication is most commonly encountered in groups where tuberculosis is prevalent. The wide availability of the drug has led to a number of reports regarding accidental or intentional acute poison ings after excessive ingestion (2 ).
