ABSTRACT
Metalloproteins constitute between one-third and one-half of the proteome of living organisms (Thomson and Gray 1998; Harding, Nowicki, and Walkinshaw 2010), and around 40% of the proteins deposited in the Protein Data Bank contain metals (Harding, Nowicki, and Walkinshaw 2010). Among many essential structural and biological functions, they are crucial in respiration and photosynthesis, participate in DNA and RNA processing, and are involved in pharmacologically important reactions, such as metabolism of xenobiotics, antibiotic resistance, or defense against
3.1 Introduction ....................................................................................................95 3.2 Methodology ...................................................................................................96
