ABSTRACT
Breast cancer is the leading incident cancer and the second leading cause of cancer death among American women (Jemal et al., 2009). An American woman has a one in eight chance of being diagnosed with breast cancer over her lifetime (Mahoney et al., 2008). Established risk factors for breast cancer include age, family history, early age at menarche, late age at menopause, nulliparity, late age at rst live birth, no breastfeeding history, increased breast density, and BRCA1 and BRCA2 mutations (Mahoney et al., 2008). Many of these are related to lifetime estrogen exposure which is believed to be causally related to breast carcinogenesis. However, most of these risk factors are not amenable to interventions as a means to prevent breast cancer occurrence.
