ABSTRACT

Image registration is the process of œnding a transformation that aligns two images. It is widely used in many œelds, including video compression, motion tracking, and medical imaging. Medical image registration is a central component in medical image analysis and has been applied widely to follow disease progression, to assess response to therapy, or to compare populations. In this chapter, the basic idea of medical image registration is introduced, and the mathematical aspects of commonly used registration techniques are explained. Applications in preclinical and clinical cancer research are also reviewed and discussed.