ABSTRACT

Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, Bayesian Adapti

chapter 1|18 pages

Statistical approaches for clinical trials

chapter 2|68 pages

Basics of Bayesian inference

chapter 3|50 pages

Phase I studies

chapter 4|56 pages

Phase II studies

chapter 5|56 pages

Phase III studies

chapter 6|32 pages

Special topics