ABSTRACT

The controlled manipulation of biological samples and the liquids they are dispersed in is a large research šeld within lab-on-a-chip systems. As society is pushing toward faster, cheaper, and reliable biochemical analysis of patient samples, research has been concentrating on miniaturizing existing processes in small chips, thus reducing analysis time and sample volume. This procedure, however, increases the need for

3.1 Understanding the Concept ............................................................................ 42 3.1.1 Governing Equations .......................................................................... 43

3.1.1.1 Case of a Spherical Particle ................................................. 45 3.1.1.2 Case of a Prolate Ellipsoid ................................................... 47 3.1.1.3 Case of a Multilayered Particle ............................................ 49

3.2 Particle Sorting ...............................................................................................50 3.2.1 Sorting of Particles with Largely Different Dielectric Properties ...... 51 3.2.2 Multiple Frequency Dielectrophoresis ................................................ 53 3.2.3 DEP/Gravitational Field Flow Fractionation ......................................54