ABSTRACT
Epilepsy is one of the most common chronic disorders of the central nervous system, leading to severe shortcomings in quality of life in about 1% of the world’s population. Abnormal synchronization of discharges of epileptogenic tissue may involve extended brain areas and provoke seizures with subjective as well as objective symptoms like the loss of motor control and consciousness. About 30% of all epilepsy patients cannot be treated adequately by continuous antiepileptic medication. Surgical resection of the epileptogenic brain tissue as a means for epilepsy treatment is only applicable in a subgroup of patients. Therefore, a reliable prediction of epileptic seizures could enable novel therapeutic strategies. If the time of seizure onset could be predicted in a timely manner, the patient could be alerted or a short-term intervention would become possible.
