ABSTRACT
This chapter serves as the foundation of the entire book, which describes in detail a nonlinear Newton method based on DOT inverse strategy in the framework of the nite element method in both frequency and continuouswave (CW) domains. The reconstruction algorithms presented have made history in the eld of DOT and have been the cornerstone for many of the DOT laboratories worldwide. Some of the milestone contributions include, for example, the rst experimental demonstrations of quantitative DOT and simultaneous recovery of absorption and scattering coefcients in heterogeneous turbid media (Jiang et al. 1995, 1996), as well as the rst reports of in vivo breast and joint imaging in both frequency and CW domain (Pogue et al. 2001, Jiang et al. 2002, Xu et al. 2002a). To date, the reconstruction algorithms have been tested or evaluated using thousands of tissue-like phantom and in vivo experiments.
