ABSTRACT
Pharmacokinetics and its related elds have numerous applications in all stages of the drug development process. This includes studying of the drug pharmacokinetic behavior in different animal species, which can be utilized to predict the absorption, distribution, metabolism, and elimination of the drug in humans. Also, designing and preparing a suitable dosage forms of the drug for use in the preclinical and clinical phases of drug development. Moreover, identication of the range of blood drug concentration, which is associated with the optimal therapeutic effect and minimum toxicity. In addition to determination of the factors that affect the drug pharmaco kinetic behavior in the different patient populations, which is important for individualiza tion of drug therapy to achieve the optimal therapeutic outcome in all patients. The following discussion covers a brief introduction to the general principles of the eld of pharmacokinetics and its related elds.
