ABSTRACT
Asthma and chronic obstructive pulmonary disease (COPD) are widely recognized as chronic airway inŠammatory lung diseases characterized by cellular in™ltration, airway remodeling, bronchoconstriction, hypermucous secretion, and declined lung function. Phospholipase A2 (PLA2) enzymes are central mediators of inŠammatory responses. Within the subfamily of PLA2, cytosolic PLA2 begins the conversion of
10.1 Introduction .................................................................................................. 239 10.2 Lipid Pathway and Production of PAF .........................................................240
