ABSTRACT

ABSTRACT: Translational medicine is an expanding area of modern medicine. It embodies the collaboration between basic science and clinical medicine, the purpose of which is to deepen our insight into disease pathogenesis and prognosis in order to advance and reˆne therapeutics. The ultimate aim of translational medicine is to individualize care by tailoring therapy to best ˆt each person and his or her speciˆc disease. Much of this approach to medicine involves the use of molecular techniques to study genetics, gene expression, and signaling pathways, while incorporating innovations in modern technology from the computer industry. Therefore, this form of medicine is also called molecular medicine. The management of thyroid cancer involves many challenges and uncertainties relating to disease development, diagnosis, and management. In this chapter, we discuss some of the molecular biology techniques involved in the study of thyroid cancer and the important role of translational medicine in revolutionizing thyroid cancer care.