ABSTRACT

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Molecules that can be recognized by a specic immune response are referred to as antigens. However, not all antigens are immunogens. Immunogens are molecules that elicit a humoral and/or a cell-mediated immune response. Some smaller molecules (haptens) are unable to stimulate an immune response, unless they are coupled to a larger reactive substance (carrier). Thus, immunogen and antigen are distinct, yet related, terms. For an antigen to elicit an antibody response, it also must be an immunogen.