ABSTRACT

As drug development shifts over time to address unmet medical needs and more targeted therapies are developed, previously unseen pharmacological or off-target effects may occur in treatment. Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical drug research, Toxicologic Pathology: Nonclinical Saf

chapter 1|22 pages

- Overview of Drug Development

chapter 2|30 pages

- Nonclinical Safety Evaluation of Drugs

chapter 3|22 pages

- Toxicokinetics and Drug Disposition

chapter 4|20 pages

- Introduction to Toxicologic Pathology

chapter 6|42 pages

- Principles of Clinical Pathology

chapter 7|34 pages

- Toxicogenomics in Toxicologic Pathology

chapter 9|56 pages

- Gastrointestinal Tract

chapter 10|54 pages

- Liver, Gallbladder, and Exocrine Pancreas

chapter 11|54 pages

- Respiratory System

chapter 12|64 pages

- Urinary System

chapter 13|32 pages

- Hematopoietic System

chapter 14|44 pages

- Lymphoid System

chapter 15|28 pages

- Bone, Muscle, and Tooth

chapter 16|66 pages

- Cardiovascular System

chapter 17|62 pages

- Endocrine Glands

chapter 18|114 pages

- Reproductive System and Mammary Gland

chapter 19|64 pages

- Skin

chapter 20|36 pages

- Nervous System

chapter 21|38 pages

- Special Senses: Eye and Ear