ABSTRACT
Bone is the only tissue able to undergo spontaneous regeneration and to remodel its micro-and macrostructure. is is accomplished through a delicate balance between osteogenic (bone-forming) and osteoclastic (bone-removing) processes (Brighton 1984; Kakar and Einhorn 2009). Bone can adapt to a new mechanical environment by changing the equilibrium between osteogenesis and osteoclasis. ese processes will respond to changes in the static and dynamic stress applied to bone; that is, if more stress than the physiological is applied, then the equilibrium tilts toward more osteogenic activity. Conversely, if less stress is applied, then the equilibrium tilts toward osteoclastic activity (it is known as the Wollf ’s law of bone remodeling) (Wol 1986).
