ABSTRACT
Aging is a heterogeneous process that affects every organ, tissue, and cell in living organisms, albeit to variable extents. The biological changes associated with age progression are results of dynamic and active processes that adapt the organism to diminishing physiological reserves in efforts to preserve functionality, with a steady progression toward an increased vulnerability to diseases. With rapid technological advances, it is now possible to explore and identify the diverse subcellular and molecular changes that underlie the phenomenological alterations in function at the organ and whole-organism levels. In this chapter, we will focus on the inuence of aging and nutrient-related signaling pathways on adult stem cell populations and discuss potential molecular events connecting these entities.
