ABSTRACT
Dengue is an old disease known by numerous household names: break-borne fever, dandy fever, three-day fever, seven-day fever, or giraffe fever, to name a few (Simmons, 1931a). Historically, dengue epidemics have occurred in cycles, sporadically emerging and re-emerging throughout the past. Recently, dengue has become one of the fastest spreading human diseases in the world. It is now endemic in over 100 countries, though initially and mainly centralized in tropical and subtropical
26.1 Introduction .......................................................................................................................... 481 26.2 Biology of the Dengue Virus ................................................................................................ 483
26.2.1 Family of Dengue Virus ........................................................................................... 483 26.2.2 Biological Properties of Dengue Virus ..................................................................... 483 26.2.3 Tissue Culture Infections ..........................................................................................484 26.2.4 In Vivo Infections .....................................................................................................485 26.2.5 Morphology of Dengue Viral Particles ....................................................................485 26.2.6 Stages of Life Cycle ..................................................................................................486
