ABSTRACT

A huge gap is emerging between the new chemicals being produced and their toxicological information that is available to us. The Office of Toxic Substances (OTS) of the United States Environmental Protection Agency (EPA) had listed around 70,000 industrial chemicals in the 1990s, with around 1000 chemicals added each year for which there is little or no toxicological information available, as mentioned in an article by Polishchuk et al. [1]. Polishchuk et al. also went ahead and mentioned in the same article that more than 30,000 of these compounds are manufactured at the rate of more than a ton per year. Moreover, humans are regularly exposed to a lot of these chemicals (10,000-30,000) in the form of water contaminants, antimicrobials, pesticide active and inert ingredients, or other forms [2-4]. Hence, there is an urgent need to obtain the toxicological information for these chemicals.