ABSTRACT

Witha-2,24-Dienolide): A Withanolide .................................................................... 316 13.4.3 Crystal Structure of Withanone (6α,7α-Epoxy-5α,17α, Dihydroxy-1-Oxo-22R-

Witha-2,24-Dienolide): A Withanolide .................................................................... 319 13.4.4 Crystal Structure of 6α,7α:24α,25α-Diepoxy-5α,12α, Dihydroxy-1-Oxo-20S,

22R-Witha-2-Enolide Methanol Solvate: A Withanolide ......................................... 322 13.4.5 Crystal Structure of (20R,22R)-6α,7α-Epoxy-5α,27-Dihydroxy-1-

Oxowitha-2,24-Dienolide: A Withanolide ................................................................ 325 13.4.6 Crystal Structure of 6α,7α-Epoxy-5α,17α,27-Trihydroxy-1-Oxo-22R-

Witha-2,24-Dienolide Monohydrate: A Withanolide ............................................... 327

Steroids constitute a very large group of natural and synthetic compounds with a broad range of biological activities. The basic steroid nucleus consists of three fused cyclohexane rings and one cyclopentane ring as shown in Figure 13.1, which illustrates the standard steroid numbering and ring nomenclature.