ABSTRACT

Introduction 813

Radiotherapy equipment and physics 813

Biological effects of radiation: DNA damage and repair 815

Tumour cell kinetics and response to radiotherapy 816

Treatment morbidity 817

Radiotherapy fractionation 820

Factors influencing the effectiveness of radiotherapy 822

New developments 823

Reirradiation 825

Key evidence 825

Key learning points 825

References 825

Let the wise listen and add to their learning and let the discerning get guidance.