ABSTRACT

An acquired form of this disorder also exists and is, in fact, much more common than the heritable form of the syndrome. Acquired LQTS is the result of a drug interaction between a drug and one of the channels that controls the orderly sequence of depolarization within the heart’s individual cardiomyocytes. This structure in question is called the ‘rapid delayed repolarizing channel’, abbreviated as hERG. The molecular structure of the hERG channel is shown in Figure 21.2.