ABSTRACT

This accounts for 2 per cent of all malignancies with over 7000 cases each year in the UK and over 3000 deaths per year. It is more common in males than females. The incidence is high in Europe, particularly Denmark, and lowest in Japan and an overall increase in incidence has been reported worldwide, much of which is attributed to increased access to investigations such as abdominal CT scan, which can identify previously occult disease.