ABSTRACT
The previous chapter began a discussion of the toxicokinetic phase. This phase consists of movement (Greek: kinesis) of a poison in the body, including absorption into the circulatory system, distribution among tissues including sites of action, and elimination from the body. This chapter focuses in more detail on the aspect of elimination that involves the loss of the parent drug from the body due to biotransformation of the parent drug to metabolites. This biotransformation generally aids in the excretion of the parent drug in the urine or feces.
