ABSTRACT
Having satisfied yourself that the reaction has run to completion or that it is time to end the experiment, the appropriate “quench” is added to the reaction mixture. Choice of this reagent can be crucial and can greatly affect the isolated yield of desired product. It is also vital to use a quench reagent or procedure that is safe. If the product is expected to be reasonably stable, which usually is the case, then the choice of procedure for quenching the reaction is determined by the reagent(s) used in the reaction. Clearly, we cannot cover all possibilities in this chapter, but general procedures that should cover most of the situations that are likely to be encountered are provided in Section 10.2. The classification is made on the basis of the nature of the reaction mixture that is to be worked up.
