ABSTRACT

All institutions, whether academic or private, develop animal use applications or protocols that request information based on the elements that are required by the Animal Welfare Act Regulations (AWRs), the Public Health Service Policy on Humane Care and Use of Laboratory Animals (PHS Policy), the Guide for the Care and Use of Laboratory Animals (Guide), and the U.S. Government

CONTENTS

5.1 Introduction .................................................................................................... 63 5.2 General Information .......................................................................................65 5.3 Personnel: Qualifications and Training ..........................................................65 5.4 Funding, Collaborations, Conflict of Interest .................................................66 5.5 Rationale and Purpose of Study ..................................................................... 67 5.6 Animal Use Justification .................................................................................68 5.7 Animal Subjects Information .........................................................................69 5.8 Animal Care, Housing, and Transportation ...................................................69 5.9 Animal Procedures/Experimental Design ..................................................... 71 5.10 Animal-Related Procedures ........................................................................... 72 5.11 Euthanasia/Final Disposition ..........................................................................77 5.12 Pain and Distress Categories ..........................................................................77