ABSTRACT

Cholesterol oxidation products are undoubtedly among the lipid oxidation products that most likely contribute to the development of atherosclerotic lesions in human large-and medium-sized arteries. They are known collectively as oxysterols, and their importance stems not only from the quantitative impact of cholesterol and its esters on the lipid-metabolism-dependent effects on atherosclerosis, but also from the various signicant biochemical properties exhibited by this class of compounds.