ABSTRACT
Maibach and Johnson defined the contact urticaria syndrome as a biological entity in 1975 (l). Contact urticaria is an immediate contact reaction that appears on the skin within minutes to an hour after an eliciting substance has been in contact with the skin. The prototype reaction of contact urticaria is a local wheal and flare, although other reactions such as nonspecific symptoms (itching. tingling, burning). generalized urticaria, and anaphylaxis occur (Table I) (2).
