Nebulized antibiotics in cystic fibrosis and non-CF bronchiectasis in children and adults A Kevin Webb, Mary E Dodd and Andrew Bush

Survival for patients with cystic fibrosis (CF) now extends into the fourth decade of life. Morbidity and mortality for this lethal disease are almost entirely related to progressive pulmonary sepsis.1,2 It is the aggressive and informed use of oral, inhaled and intravenous antibiotics against the organisms which infect the CF lung, which have transformed this lethal disease from one leading to death in childhood to survival into adulthood.3,4 The care of CF patients is complex and the judicious use of antibiotics for these patients is best delivered by a multidisciplinary team in a CF center.5