ABSTRACT
Since cancer usually arises in the peripheral zone of the prostate, when a small nodule is felt on rectal examination it is better to get tissue for histology by means of a transrectal biopsy, a procedure which today is most accurately performed under transrectal ultrasound control1,2. The later management of the small prostatic nodule is still a matter for debate which is beyond the scope of this monograph, and unfortunately is of little relevance to the large number of men who present at a stage when their cancer is not confined to the prostate, but is causing severe symptoms from outflow obstruction.
