ABSTRACT
Concepts of stability in the vertebral column are complex and frequently confusing. The vertebral column serves to transmit loads, permit motion, and protect the spinal cord. The pathological outcome of trauma to the spinal cord is related to a “primary” mechanical injury at the epicenter of the damage. Cardiovascular and pulmonary compromise may affect perfusion and oxygen delivery to the spinal cord, exacerbating the damage and therefore worsening secondary Spinal Cord Injury (SCI). Delayed spinal cord compression may also develop from a hematoma within the spinal canal or movement of bone or prolapsed disk in a spine that is not properly immobilized. Animal models of SCI have offered the hope that damage caused by secondary injury can be mitigated by early pharmacological intervention. Radiologically proven compression of the spinal cord and nerve roots mandates surgical intervention for decompression and stabilization in the patient with incomplete SCI.
