ABSTRACT
There is a substantial literature from the 1970s, often overlooked by many present workers, on the physical chemistry of lipid bilayer systems, which have laid the foundation for studying lateral organization and lipid domains in membranes (for a critical review, see Ref. 1). Early evidence that lipids could laterally segregate in model membrane systems under certain conditions and form different lipid domains with particular structural characteristics (i.e., different lateral packing) was reported in 1970 by Phillips et al.,2 who assessed, using differential scanning
1.1 Membrane Domains: A Historical Overview ...................................................3 1.2 Lateral Structure and Dynamics of Lipid Bilayers ...........................................6
