ABSTRACT
Retinoids and hydroxy acids have successfully been used as active ingredients to improve the appearance of aging skin. However, both retinoids and hydroxy acids may be associated with skin irritation, stimulating a search for alternatives. Possible alternatives include kinetin (N6-furfuryladenine), zeatin, and pyratine-6. Kinetin and zeatin are members of a plant growth hormone family known as cytokinins, which have growth-promoting and antiaging effects in plants. Pyratine-6 (furfurylaminotetrahydropyranyladenine) is a synthetic analog of kinetin. The incorporation of these materials into cosmeceuticals is reviewed here.
