ABSTRACT
HUS was rst described by Gasser in 1955, and the systemic character of HUS was subsequently dened.1 Kaplan and Drummond2 identied several distinct entities that can manifest as HUS and emphasized that HUS was a syndrome with a common pathologic outcome. HUS is now considered as a part of the broader group of TMA. TTP, rst described by Moschcowitz3 in 1925, is a distinct clinicopathologic condition that can mimic the clinical characteristics of HUS. Indeed, although these criteria seem distinct, in real life the clinical forms are oen incomplete or changing during the
course of the disorder, complicating a precise separation of the two entities and their evaluation and treatment.
