ABSTRACT
There has been a rapid thrust in research to unlock mysteries of human brain function spanning several disciplines. Neuroimaging technology provides invaluable tools, which have led
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to major advancements in our understanding of the brain, with contributions from fields such as neuroscience, psychiatry, neurology, radiology, psychology, statistics, computer science, and biomedical and electrical engineering, among others. The intricate neuroanatomical structure of the brain plays an integral role in supporting brain function, and it independently sheds light on disease and plasticity. While the interdependence between functional and structural properties of the brain is well accepted, current imaging technology that we probe typically yields properties reflecting either structure or function. There is emerging interest and an unmet need to consider joint modeling of data in pursuit of discoveries about normal brain function, disease-related alterations, and the response to treatment for such disorders.
