ABSTRACT

This chapter presents classification & mode of action, indications & dermatological uses, formulations/presentation, dosages & suggested regimens, baseline investigations, considerations & monitoring, contraindications, cautions, important drug interactions, adverse effects & their management, use in special situations, and essential patient information of Potassium Iodide (KI). Deficiency of iodine leads to ‘endemic goitre’, intellectual and developmental disabilities, which can be prevented by the routine addition of iodine to dietary salt in the form of KI or potassium iodate. KI was first isolated in seaweed in the 19th century, and thereafter it was used to treat both thyroid disorders and various dermatological and infective diseases. KI is well-absorbed orally and distributed selectively into thyroid gland. The exact mechanism of action of KI in inflammatory dermatological diseases is not understood, but is thought to be immunomodulatory. KI is a thyroid-blocking agent and is licensed for the treatment of thyrotoxicosis. Solutions of KI are used as expectorants to reduce the stickiness of mucous in chest complaints.