ABSTRACT
INTRODUCTION: IMPORTANCE OF LANGERHANS CELLS IN RELATION TO PEELING SIDE EFFECTS In 1968, Paul Langerhans discovered the presence of a particular type of epidermal cell in humans, which is now named after him. The Langerhans cell (LC) is a mobile dendritic cell that has no desmosomes and is found in most multilayered malpighian epithelia. LCs make up 2%–5% of epidermal cells. They come from the medulla, migrate toward and within the skin, and stay within the epidermis for 2 weeks at the most.
