ABSTRACT
The anatomy of the external ear canal is such that liquid medications, in excess, will tend to pool in the horizontal canal. High concentrations of medication may thus come into contact with inflamed epithelium and the potential for intraand percutaneous absorption is readily apparent. In some circumstances this is desirable. For example, the anti-inflammatory effect of a topical glucocorticoid must be exerted on dermal tissues. In contrast, an antimicrobial, antifungal, or acaricidal agent will usually be applied to the external ear canal for their topical effect and absorption is not necessary.
