ABSTRACT
Inammation and immune response are traditionally thought to be a process governed on a cellular level through complicated autocrine and paracrine feedback mechanisms. For example, the standard response to infection consists of local antigen-presenting cells inducing an acute response from the innate immune system (namely, phagocytic cells), which then stimulates T cells and B cells to mount an adaptive immune response. The initial pro-inammatory response generates an antiinammatory reaction during the adaptive immune response from Th2 and Treg activated T cells, which restores homeostasis in a self-regulating cytokine-based system.
